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Adenovirus Vectors and Subviral Particles for Protein and Peptide Delivery

[ Vol. 12 , Issue. 5 ]

Author(s):

Matthias W. Kron and Florian Kreppel   Pages 362 - 373 ( 12 )

Abstract:


Adenovirus vectors belong to the most frequently used vector type in gene therapy approaches. In addition, adenovirus vector particles and adenovirus subviral particles offer a great potential for the direct delivery of proteins into cells. In this review we discuss this potential and the technology of adenovirus as a protein delivery platform for applications ranging from vaccination to gene therapy.

Keywords:

Protein delivery, adenovirus vector, adenovirus subviral particles, peptide delivery, gene transfer vectors, vector capsids, epidermal growth factor, endosomal

Affiliation:

Department of Gene Therapy, University of Ulm, Helmholtzstr. 8/1, D-89081 Ulm, Germany.



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